Novel compact magnetless isolator based on a magneto-optical garnet material

A compact magnetless isolator for optical communication systems based on a ring resonator with an outer layer made of silicon and an inner layer made of a magneto-optical material that does not require an external magnet to keep its magnetization saturated is suggested. Three-dimensional computational simulations of the device performed with the full-wave electromagnetic solver COMSOL Multiphysics show that the insertion loss and isolation levels are about −1.9 dB and −23 dB, respectively, thus confirming the feasibility of the isolator. An analytical model of the device based on the temporal coupled-mode theory method has been formulated and there is a good agreement between the analytical and simulation results. Since it does not require a magnetization scheme based on permanent magnets or electromagnets as conventional isolators do, the presented isolator is much more compact, with a footprint at least one order of magnitude smaller in comparison with other isolator designs known from the literature, and this feature makes the suggested device an ideal candidate for optical circuits with very high integration density

On the Localized superluminal Solutions to the Maxwell Equations

In the first part of this article the various experimental sectors of physics in which Superluminal motions seem to appear are briefly mentioned, after a sketchy theoretical introduction. In particular, a panoramic view is presented of the experiments with evanescent waves (and/or tunneling photons), and with the "Localized superluminal Solutions" (SLS) to the wave equation, like the so-called X-shaped waves. In the second part of this paper we present a series of new SLSs to the Maxwell equations, suitable for arbitrary frequencies and arbitrary bandwidths: some of them being endowed with finite total energy. Among the others, we set forth an infinite family of generalizations of the classic X-shaped wave; and show how to deal with the case of a dispersive medium. Results of this kind may find application in other fields in which an essential role is played by a wave-equation (like acoustics, seismology, geophysics, gravitation, elementary particle physics, etc.). This e-print, in large part a review, was prepared for the special issue on "Nontraditional Forms of Light" of the IEEE JSTQE (2003); and a preliminary version of it appeared as Report NSF-ITP-02-93 (KITP, UCSB; 2002). Further material can be found in the recent e-prints arXiv:0708.1655v2 [physics.gen-ph] and arXiv:0708.1209v1 [physics.gen-ph]. The case of the very interesting (and more orthodox, in a sense) subluminal Localized Waves, solutions to the wave equations, will be dealt with in a coming paper. [Keywords: Wave equation; Wave propagation; Localized solutions to Maxwell equations; Superluminal waves; Bessel beams; Limited-dispersion beams; Electromagnetic wavelets; X-shaped waves; Finite-energy beams; Optics; Electromagnetism; Microwaves; Special relativity]Comment: LaTeX paper of 37 pages, with 20 Figures in jpg [to be processed by PDFlatex

Wireless link evaluation of a dielectric resonator nanoantenna

Optical antennas/nanoantennas are optical elements that have gained highlight in this decade and have potential application in several branches of photonics/plasmonics, such as, optical sensors, lasers, solid state lighting, photovoltaics, microscopy, etc. Additionally, the dipole nanoantennas have been the antennas elements mostly studied in proposals for those applications and, in special, for free-space communication based on plasmonic circuits. Here we report some advantages of dielectric resonator nanoantennas (DRNAs) as elements for coupling light to plasmonic-based circuits. Fundamental antenna parameters such as reflection coefficient, gain, efficiency, among others, are evaluated and its advantages are highlighted for nanophotonics applications. A study about an optical link for circuits based on metal-dielectric-metal-dielectric (MDMD) nanostrip waveguides operating at the central wavelength of λ0 = 1.55 μm is evaluated. We studied the coupling of near- and far-fields of a DRNA matched to an MDMD nanostrip waveguide. The results show the advantage of it as an element for optical coupling from/to free-space as well as to establish a wireless optical link for inter-chip communication10924SPIE OPTO - Optical Interconnects XI

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362